Metabolic Pathway: ec00010

Glycolysis / Gluconeogenesis

KEGG

1 Pathways and interactions

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Node Details

EC Number or Reaction: 5.4.2.2

Enzyme Name: Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)

Show 73 gene(s) which match this EC Number

Search on OrthoMCL for groups with this EC Number

Data Sets

Showing 61 rows

Reaction Source	EC Number	Enzyme Description	Equation	Gene Count
KEGG	1.1.1.1	Alcohol dehydrogenase	ethanol <=> acetaldehyde	0
KEGG	1.1.1.2	Alcohol dehydrogenase (NADP(+))	ethanol <=> acetaldehyde	0
KEGG	1.1.1.27	L-lactate dehydrogenase	(S)-lactate <=> pyruvic acid	128
KEGG	1.1.2.7	Methanol dehydrogenase (cytochrome c)	ethanol <=> acetaldehyde	0
KEGG	1.1.2.8	Alcohol dehydrogenase (cytochrome c)	ethanol <=> acetaldehyde	0
KEGG	1.1.5.5	Alcohol dehydrogenase (quinone)	ethanol => acetaldehyde	0
KEGG	1.2.1.12	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	D-glyceraldehyde 3-phosphate <=> 3-phospho-D-glyceroyl dihydrogen phosphate	43
KEGG	1.2.1.12	Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	3-phospho-D-glyceroyl dihydrogen phosphate + D-glyceraldehyde 3-phosphate <=> 3-phospho-D-glyceroyl dihydrogen phosphate + D-glyceraldehyde 3-phosphate	43
KEGG	1.2.1.3	Aldehyde dehydrogenase (NAD(+))	acetaldehyde <=> acetate	0
KEGG	1.2.1.5	Aldehyde dehydrogenase (NAD(P)(+))	acetaldehyde <=> acetate	0
KEGG	1.2.1.59	Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating)	3-phospho-D-glyceroyl dihydrogen phosphate + D-glyceraldehyde 3-phosphate <=> 3-phospho-D-glyceroyl dihydrogen phosphate + D-glyceraldehyde 3-phosphate	0
KEGG	1.2.1.9	Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))	D-glyceraldehyde 3-phosphate => 3-phospho-D-glyceric acid	0
KEGG	1.2.1.90	Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+))	D-glyceraldehyde 3-phosphate => 3-phospho-D-glyceric acid	0
KEGG	1.2.4.1	Pyruvate dehydrogenase (acetyl-transferring)	Enzyme N6-(lipoyl)lysine + 2-(1-hydroxyethyl)thiamine diphosphate => [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + thiamine(1+) diphosphate	90
KEGG	1.2.4.1	Pyruvate dehydrogenase (acetyl-transferring)	pyruvic acid + thiamine(1+) diphosphate => 2-(1-hydroxyethyl)thiamine diphosphate	90
KEGG	1.2.7.1	Pyruvate synthase	carbon dioxide + pyruvic acid => acetyl-CoA	0
KEGG	1.2.7.11	2-oxoacid oxidoreductase (ferredoxin)	pyruvic acid => acetyl-CoA	0
KEGG	1.2.7.6	Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)	D-glyceraldehyde 3-phosphate => 3-phospho-D-glyceric acid	0
KEGG	1.8.1.4	Dihydrolipoyl dehydrogenase	Enzyme N6-(dihydrolipoyl)lysine + Enzyme N6-(dihydrolipoyl)lysine <=> Enzyme N6-(lipoyl)lysine + Enzyme N6-(lipoyl)lysine	90
KEGG	2.3.1.12	Dihydrolipoyllysine-residue acetyltransferase	acetyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine	46
KEGG	2.7.1.-	Phosphotransferases with an alcohol group as acceptor.	salicin => salicin 6-phosphate	2166
KEGG	2.7.1.-	Phosphotransferases with an alcohol group as acceptor.	hydroquinone O-beta-D-glucopyranoside => arbutin 6-phosphate	2166
KEGG	2.7.1.1	Hexokinase	alpha-D-glucose + alpha-D-glucose <=> alpha-D-glucose 6-phosphate + alpha-D-glucose 6-phosphate	28
KEGG	2.7.1.1	Hexokinase	beta-D-glucose => beta-D-glucose 6-phosphate	28
KEGG	2.7.1.11	6-phosphofructokinase	beta-D-fructofuranose 6-phosphate <=> beta-D-fructofuranose 1,6-bisphosphate	76
KEGG	2.7.1.146	ADP-specific phosphofructokinase	beta-D-fructofuranose 6-phosphate => beta-D-fructofuranose 1,6-bisphosphate	46
KEGG	2.7.1.147	ADP-specific glucokinase	alpha-D-glucose => alpha-D-glucose 6-phosphate	0
KEGG	2.7.1.147	ADP-specific glucokinase	beta-D-glucose <=> beta-D-glucose 6-phosphate	0
KEGG	2.7.1.199	Protein-N(pi)-phosphohistidine--D-glucose phosphotransferase	D-glucopyranose => alpha-D-glucose 6-phosphate	0
KEGG	2.7.1.2	Glucokinase	alpha-D-glucose + alpha-D-glucose <=> alpha-D-glucose 6-phosphate + alpha-D-glucose 6-phosphate	0
KEGG	2.7.1.2	Glucokinase	beta-D-glucose => beta-D-glucose 6-phosphate	0
KEGG	2.7.1.40	Pyruvate kinase	ATP + pyruvic acid + phosphoenolpyruvic acid <=> ADP + pyruvic acid + phosphoenolpyruvic acid	90
KEGG	2.7.1.63	Polyphosphate--glucose phosphotransferase	beta-D-glucose => beta-D-glucose 6-phosphate	0
KEGG	2.7.1.63	Polyphosphate--glucose phosphotransferase	alpha-D-glucose => alpha-D-glucose 6-phosphate	0
KEGG	2.7.1.90	Diphosphate--fructose-6-phosphate 1-phosphotransferase	beta-D-fructofuranose 6-phosphate <=> beta-D-fructofuranose 1,6-bisphosphate	45
KEGG	2.7.2.3	Phosphoglycerate kinase	3-phospho-D-glyceric acid + 3-phospho-D-glyceric acid <=> 3-phospho-D-glyceroyl dihydrogen phosphate + 3-phospho-D-glyceroyl dihydrogen phosphate	45
KEGG	3.1.3.10	Glucose-1-phosphatase	alpha-D-glucose + alpha-D-glucose 1-phosphate <=> alpha-D-glucose + alpha-D-glucose 1-phosphate	0
KEGG	3.1.3.11	Fructose-bisphosphatase	beta-D-fructofuranose 1,6-bisphosphate => beta-D-fructofuranose 6-phosphate	0
KEGG	3.1.3.80	2,3-bisphosphoglycerate 3-phosphatase	2,3-bisphospho-D-glyceric acid <=> 2-phospho-D-glyceric acid	0
KEGG	3.1.3.9	Glucose-6-phosphatase	alpha-D-glucose 6-phosphate <=> alpha-D-glucose	0
KEGG	3.2.1.86	6-phospho-beta-glucosidase	arbutin 6-phosphate => beta-D-glucose 6-phosphate	0
KEGG	3.2.1.86	6-phospho-beta-glucosidase	salicin 6-phosphate => beta-D-glucose 6-phosphate	0
KEGG	4.1.1.1	Pyruvate decarboxylase	pyruvic acid + thiamine(1+) diphosphate => 2-(1-hydroxyethyl)thiamine diphosphate	0
KEGG	4.1.1.1	Pyruvate decarboxylase	2-(1-hydroxyethyl)thiamine diphosphate <=> acetaldehyde	0
KEGG	4.1.1.32	Phosphoenolpyruvate carboxykinase (GTP)	oxaloacetic acid + oxaloacetic acid <=> phosphoenolpyruvic acid + phosphoenolpyruvic acid	0
KEGG	4.1.1.49	Phosphoenolpyruvate carboxykinase (ATP)	oxaloacetic acid + oxaloacetic acid <=> carbon dioxide + phosphoenolpyruvic acid + phosphoenolpyruvic acid	45
KEGG	4.1.2.13	Fructose-bisphosphate aldolase	beta-D-fructofuranose 1,6-bisphosphate <=> glycerone phosphate + D-glyceraldehyde 3-phosphate	45
KEGG	4.2.1.11	Phosphopyruvate hydratase	2-phospho-D-glyceric acid <=> phosphoenolpyruvic acid	45
KEGG	5.1.3.15	Glucose-6-phosphate 1-epimerase	alpha-D-glucose 6-phosphate <=> beta-D-glucose 6-phosphate	0
KEGG	5.1.3.3	Aldose 1-epimerase	alpha-D-glucose <=> beta-D-glucose	0
KEGG	5.3.1.1	Triose-phosphate isomerase	glycerone phosphate + D-glyceraldehyde 3-phosphate <=> glycerone phosphate + D-glyceraldehyde 3-phosphate	91
KEGG	5.3.1.9	Glucose-6-phosphate isomerase	alpha-D-glucose 6-phosphate <=> beta-D-fructofuranose 6-phosphate	46
KEGG	5.3.1.9	Glucose-6-phosphate isomerase	beta-D-glucose 6-phosphate <=> beta-D-fructofuranose 6-phosphate	46
KEGG	5.3.1.9	Glucose-6-phosphate isomerase	alpha-D-glucose 6-phosphate <=> beta-D-glucose 6-phosphate	46
KEGG	5.4.2.11	Phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)	2,3-bisphospho-D-glyceric acid <=> 3-phospho-D-glyceric acid	89
KEGG	5.4.2.11	Phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)	2-phospho-D-glyceric acid + 2-phospho-D-glyceric acid <=> 3-phospho-D-glyceric acid + 3-phospho-D-glyceric acid	89
KEGG	5.4.2.12	Phosphoglycerate mutase (2,3-diphosphoglycerate-independent)	2-phospho-D-glyceric acid + 2-phospho-D-glyceric acid <=> 3-phospho-D-glyceric acid + 3-phospho-D-glyceric acid	0
KEGG	5.4.2.2	Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)	alpha-D-glucose 1-phosphate <=> alpha-D-glucose 6-phosphate	73
KEGG	5.4.2.4	Bisphosphoglycerate mutase	3-phospho-D-glyceroyl dihydrogen phosphate <=> 2,3-bisphospho-D-glyceric acid	0
KEGG	6.2.1.1	Acetate--CoA ligase	acetate <=> acetyl-CoA	45
KEGG	6.2.1.13	Acetate--CoA ligase (ADP-forming)	acetyl-CoA + acetate <=> acetyl-CoA + acetate	0

This table shows pathways that share at least two reactions with the pathway displayed on this page. Default ordering is by the percentage of reactions in the smaller pathway that are shared between the two pathways.

Showing 62 rows

Matched Pathway	Pathway Source	Total Reactions in Displayed Pathway	Total Reactions in Matched Pathway	Reactions Shared Between Displayed and Matched Pathways
homolactic fermentation	MetaCyc	54	11	9
glycolysis III (from glucose)	MetaCyc	54	10	8
glycolysis IV (plant cytosol)	MetaCyc	54	10	7
ethanol degradation III	MetaCyc	54	3	2
glycolysis V (Pyrococcus)	MetaCyc	54	9	6
ethanol degradation IV	MetaCyc	54	3	2
GDP-glucose biosynthesis	MetaCyc	54	3	2
trehalose degradation V	MetaCyc	54	3	2
Rapoport-Luebering glycolytic shunt	MetaCyc	54	3	2
ethanol degradation II	MetaCyc	54	3	2
glycolysis I (from glucose 6-phosphate)	MetaCyc	54	12	8
glycolysis II (from fructose 6-phosphate)	MetaCyc	54	11	7
glucose and glucose-1-phosphate degradation	MetaCyc	54	5	3
sucrose biosynthesis I (from photosynthesis)	MetaCyc	54	9	5
gluconeogenesis I	MetaCyc	54	13	7
Bifidobacterium shunt	MetaCyc	54	15	8
superpathway of anaerobic sucrose degradation	MetaCyc	54	19	10
superpathway of glycolysis and Entner-Doudoroff	MetaCyc	54	16	8
gluconeogenesis III	MetaCyc	54	12	6
sucrose degradation IV (sucrose phosphorylase)	MetaCyc	54	4	2
sucrose degradation III (sucrose invertase)	MetaCyc	54	4	2
hexitol fermentation to lactate, formate, ethanol and acetate	MetaCyc	54	19	8
superpathway of hexitol degradation (bacteria)	MetaCyc	54	17	7
NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)	MetaCyc	54	5	2
sucrose degradation II (sucrose synthase)	MetaCyc	54	5	2
heterolactic fermentation	MetaCyc	54	18	7
sucrose biosynthesis II	MetaCyc	54	8	3
glycerol degradation to butanol	MetaCyc	54	16	6
superpathway of glucose and xylose degradation	MetaCyc	54	17	6
Entner-Doudoroff pathway III (semi-phosphorylative)	MetaCyc	54	9	3
formaldehyde assimilation III (dihydroxyacetone cycle)	MetaCyc	54	12	4
1,3-propanediol biosynthesis (engineered)	MetaCyc	54	9	3
superpathway of N-acetylneuraminate degradation	MetaCyc	54	21	7
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass	MetaCyc	54	25	8
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle	MetaCyc	54	22	7
Calvin-Benson-Bassham cycle	MetaCyc	54	13	4
Rubisco shunt	MetaCyc	54	10	3
gluconeogenesis II (Methanobacterium thermoautotrophicum)	MetaCyc	54	20	6
UDP-N-acetyl-D-galactosamine biosynthesis II	MetaCyc	54	7	2
Biosynthesis of antibiotics	KEGG	54	971	15
photosynthetic 3-hydroxybutanoate biosynthesis (engineered)	MetaCyc	54	26	7
Citrate cycle (TCA cycle)	KEGG	54	26	7
1-butanol autotrophic biosynthesis (engineered)	MetaCyc	54	27	7
superpathway NAD/NADP - NADH/NADPH interconversion (yeast)	MetaCyc	54	8	2
glycogen degradation I	MetaCyc	54	8	2
ethylene biosynthesis V (engineered)	MetaCyc	54	25	6
oxygenic photosynthesis	MetaCyc	54	17	4
Entner-Doudoroff pathway II (non-phosphorylative)	MetaCyc	54	9	2
chitin biosynthesis	MetaCyc	54	14	3
Pyruvate metabolism	KEGG	54	73	11
colanic acid building blocks biosynthesis	MetaCyc	54	10	2
starch biosynthesis	MetaCyc	54	10	2
Carbon fixation in photosynthetic organisms	KEGG	54	27	5
Carbon metabolism	KEGG	54	148	10
Pentose phosphate pathway	KEGG	54	54	9
Biosynthesis of amino acids	KEGG	54	147	9
Methanobacterium thermoautotrophicum biosynthetic metabolism	MetaCyc	54	55	6
Amino sugar and nucleotide sugar metabolism	KEGG	54	133	5
Fructose and mannose metabolism	KEGG	54	80	5
Methane metabolism	KEGG	54	101	4
Galactose metabolism	KEGG	54	55	3
Carbon fixation pathways in prokaryotes	KEGG	54	55	2

Metabolic Pathway: ec00010

Glycolysis / Gluconeogenesis

ec00010

1 Pathways and interactions§

1.1 Metabolic pathways§